Active Ingredient : Anthraquinones 1.5% & Fistulic Acid
Common Name : Fistula, Laburnum, Purging Fistula, Golden Shower
Chemical Constituents and Components : Main chemical components are anthraquinones, fistulic acid, rhein, rheinglucoside, sennosides A and B, phlobaphenes, emodin, chrysophanic acid, fistuacacidin, lupeol, beta-sitosterol and hexacosanol.
Action : Anthraquinones: 1. It decreases the amount of enzymatic cytochrome C reduction at low concentrations of NADH. 2. It shows good antineoplastic activity. 3. It inhibits the catalytic activity of topoisomerase II. 4. It shows clastogenic effect on bone marrow cell and used as weak genotoxic. Fistulic acid: 1. It significantly lowers the serum levels of transminases (SGOT and SGPT), bilirubin and alkaline phosphatase (ALP). 2. It significantly lowers the lipid level in blood and liver. 3. It significantly decrease the high activities of serum GOT, GPT, alkaline and acid phosphatase.
Curing Diseases : 1. It is used to cure erysipelas, malaria, rheumatism, syphilis and ulcers.
2. It is used in the treatment of cardiovascular diseases and cancer.
Research Information : Cassia fistula fruit pulp possesses antifungal property. Secondary metabolites present in the extract responsible for the inhibition of fungus and its growth. (Ref. Sharma K., Dak G., Nambakkat L., Kanipotth V., X-ray diffraction evidence for antifungal action of Cassia fistula linn. fruit pulp extract, ESCMID, Abstract number: r1921)
Possible Combinations : Cassia fistula + cassia angustigolia (gall stone treatment)